European Society of Neuro Radiology
International Society of Magnetic Resonance in
University of Michigan FMRI laboratory European Society for Magnetic Resonance in Medicine
              and Biology (ESMRMB)

University of Michigan International Workshop on Arterial Spin Labeling

Introduction to BASIL and ExploreASL

March 8, 2019
9 am - 4 pm
B250 East Hall
University of Michigan
Ann Arbor, MI, USA


Dr. Michael Chappell , Associate Professor, Institute of Biomedical Engineering, University of Oxford.
Dr. Henk(-Jan) Mutsaerts, MD PhD, Radiology Department, Academic Medical Center, Amsterdam, The Netherlands
The day before the workshop starts, there will be a short course intended to introduce interested workshop participants to a couple of useful ASL processing tools: 

The first part is BASIL (Bayesian Inference for Arterial Spin Labeling MRI).  BASIL is a complete toolbox for the analysis of almost any ASL data for both single subject or group studies. As part of the FRMIB Software Library it exploits a range of widely-used tools for registration, motion and distortion correction and adds a fully Bayesian inference of perfusion and other haemodynamic parameters from data from practically any ASL acquisition. BASIL is available via a graphical user interface or command line on any operating system.

The FSL-ASL mini course covers the complete process for the analysis of ASL data right, all the way from what you need to know about your acquisition, appropriate pre-processing, and perfusion quantification, to registration and group analysis. The course additionally covers more advanced topics such as partial volume correction. This min-course is a combination of lectures and hands-on exercises using the BASIL tools from FSL.
The second part is ExploreASL is a pipeline and toolbox for image processing and statistics of arterial spin labeling perfusion MR images. It is designed as a multi-OS, open source, collaborative framework that facilitates cross-pollination between image processing method developers and clinical investigators.

The software provides a complete head-to-tail approach that runs fully automatically, encompassing all necessary tasks from data import and structural segmentation, registration and normalization, up to CBF quantification. In addition, the software package includes and quality control (QC) procedures and region-of-interest (ROI) as well as voxel-wise analysis on the extracted data.

To-date, ExploreASL has been used for processing ~8000 ASL datasets from all major MRI vendors and ASL sequences, and a variety of patient populations, representing ~30 studies. The ultimate goal of Explore ASL is to combine data from multiple studies to identify disease related perfusion patterns that may prove crucial in using ASL as a diagnostic took and enhance our understanding of the interplay of perfusion and structural changes in neurodegenerative pathophysiology.
Registration:  simply send an email to:
with your name and affiliation and put the word EXPLOREASL-BASIL in the subject line of your email