News
Upcoming Visiting Speaker
Jim Haxby of the Dartmouth Center for Cognitive Neuroscience will be giving a series of talks on Feb 18-19, 2019. Monday Feb 18 3-4pmMICDE Seminar 1017 Dow (2300 Hayward Street)
Bridging the divide: fostering interdisciplinary collaborative research in computational cognitive neuroscience Tuesday Feb 19 10:30-11:30
Informal methods talk/roundtable 4464 East Hall
Current issues in computational neuroimaging of brain function Tuesday Feb 19 4-5:30pm
NII/Psychology/fMRI talk 4448 East Hall
Hyperalignment: modeling the shared information encoded in idiosyncratic fine-scale cortical topographies.
Multivariate pattern analysis reconceptualizes cortical functional architecture as high-dimensional information spaces that are encoded in fine-grained topographies of response and functional connectivity patterns. We have developed a high-dimensional computational model of the information encoded in response and connectivity topographies that is shared across brains. We derive this model with new algorithms called response hyperalignment and connectivity hyperalignment. Our model captures shared information as basis functions for response tuning and functional connectivity that are common across brains. These response and connectivity basis functions are instantiated in individual brains as multiplexed topographic basis functions that are specific to each individual brain. We developed this model using fMRI data collected while subjects watched meaningful, dynamic naturalistic stimuli, namely movies, and during the resting state. We are now investigating how this model can be leveraged for more sensitive analyses of individual differences in cortical functional architecture that predict cognitive differences.