Luis Hernandez-Garcia, Ph.D.
Research Associate Professor, Biomedical Engineering
Research Associate Professor, Functional MRI Laboratory
Facility Manager, Animal MRI Facility
2360 Bonisteel Blvd.
Ann Arbor, MI 48109-2108
Dr. Hernandez's research interests are focused on developing and integrating techniques for the study of brain function.
He has been involved in BOLD (Blood Oxygenation Level Dependent) and ASL (Arterial Spin Labeling) Functional MRI research for a number of years. Primarily, he has been developing ASL methods for quantitatively imaging cerebral perfusion. Perfusion is an indicator of brain function and therefore a very valuable tool, not just for the clinician, but also for the neuroscientist and psychologist. He is currently working on kinetic models for quantifying the ASL signal, and techniques that will improve the SNR and temporal resolution of perfusion measurements.
He is very interested in the properties of the BOLD signal and extracting as much information as possible from them. He is also interested in the non-linear temporal characteristics of the vascular response to neuronal activations, and is working on mathematical models of the BOLD response in terms of the underlying physiology. He is also interested in using the statistical properties of the BOLD signal to extract information about the hierarchical relationships between active brain regions.
Dr. Hernandez is also working on methods for modeling and measuring the electromagnetic fields produced by transcranial magnetic stimulation (TMS) devices within the brain. Using these techniques, he is trying to improve the targeting and penetration capability of TMS devices.
Finally, he has collaborated tightly with research groups in psychology and neurology in the study of attention, memory, pain and depression.